Histopathological Aspects of the Acute Acalculous Cholecystitis Experimentally Induced by Laparoscopy with L-α-phosphatidylcholine

Introduction. The experimental study aimed to induce the acute alithiasic cholecystitis in 20 pigs, injecting L-α-Phosphatidylcholine in the gallbladder using laparoscopy. Materials and methods. After the induction the laparoscopic cholecystectomy was performed after 3 and 7 days. Hematoxylin and eosin stain was done from the sections. Results. The histology emphasized the gallbladder’s inflammation, colagenolysis and vascular alteration. The laparoscopic cholecystectomy on the first group had a medium time of 71 minutes and at the second group medium time was 94 minutes. Conclusions. The experimental induction of acute acalculous cholecystitis is possible injecting using laparoscopy in the gallbladder L-αPhosphatidylcholine, the inflammatory lesions being emphasized.